In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biology of reproduction, 89(4):93,1-9 (2013). C (3-6 months) 立花　誠 条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。Biology of reproduction, 89(4):93,1-9 (2013). Jmjd1c KO, B6-Jmjd1c KO Jmjd1c KO, B6-Jmjd1c KO B6.Cg-Jmjd1c<tm1Mtac> B6.Cg-Jmjd1c<tm1Mtac> true Tachibana, Makoto ヒストン脱メチル化酵素であるJmjd1分子ファミリーの1つであるJmjd1cの遺伝子を欠損させたマウス。エクソン24から27がIRES-neoで置換されている。ホモマウスの雄は生後3～4ヶ月で精子が減少し始め、野生型に比べより早期に不妊となる。 TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] Developed by Matoko Tachibana, Institute for Virus Research, Kyoto Uiniversity in 2008. TT2 ES cells were used to generate the mutant mice. C57BL/6 semicongenic. Streptomyces fradiase neo, Encephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), Simian virus 40 polyA additional signal, mouse jumonji domain containing 1C genomic DNA <a href='https://brc.riken.jp/mus/pcr06532'>Genotyping protocol -PCR-</a> RBRC06532 Jmjd1c gene knockout mice. Exons 24 to 57 was replaced with an IRES-neo cassette. C（3〜6か月） Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> 京都大学ウィルス研究所・立花　誠先生（2008）。TT2 ES細胞を用いて作出。C57BL/6へ交配された（C57BL/6セミコンジェニック）。 Heterozygote x Wild-type [C57BL/6JJmsSlc] Heterozygote x Wild-type [C57BL/6JJmsSlc]